Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 17/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | FADS1 | O60427 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27980470 | 0.85 | PPIA (0.62) | PPIA | |
| SCHEMBL27980139 | 0.81 | PPIA (0.70) | PPIA | |
| SCHEMBL27980361 | 0.80 | PPIA (0.72) | PPIA | |
| Resorcinol SCHEMBL27980357 | 0.76 | NLRP3 (0.41) | PPIARAB9ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL27971369 | 0.76 | PPIA (1.00) | PPIA | |
| SCHEMBL27980374 | 0.75 | PPIA (1.00) | PPIA | |
| SCHEMBL28813875 | 0.75 | PPIA (1.00) | PPIA | |
| SCHEMBL27980358 | 0.73 | PPIA (1.00) | PPIAMEN1LMNAKMT2A | |
| SCHEMBL28813669 | 0.71 | PPIA (0.68) | PPIA | |
| SCHEMBL27980327 | 0.71 | PPIA (1.00) | PPIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103992245-A | Substituted urea compound and use thereof | UNIV EAST CHINA SCIENCE & TECH | 2014-08-20 | — | — | CN | disclosed |