Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Resorcinol SCHEMBL27980472 | 0.85 | PPIA (0.35) | SMN1; SMN2RAB9AHPGDALDH1A1NPC1 | |
| Resorcinol SCHEMBL27980362 | 0.83 | PPIA (0.44) | LMNAALDH1A1PPIA | |
| SCHEMBL27980356 | 0.76 | PPIA (0.60) | LMNASMN1; SMN2RAB9AHPGDNPC1 | |
| Resorcinol SCHEMBL27980376 | 0.76 | PPIA (0.60) | PPIA | |
| 1-Hydroxy-3-Ethoxybenzene SCHEMBL11135932 | 0.67 | CHRNB2 (0.58) | NLRP3LMNASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL339500 | 0.67 | LTA4H (0.57) | L3MBTL1LMNAMAPK1SMN1; SMN2HPGD | |
| 1-Hydroxy-4-Ethoxybenzene SCHEMBL11135491 | 0.66 | LTA4H (0.68) | NLRP3LMNASMN1; SMN2ALDH1A1TDP1 | |
| 1-Hydroxy-3-Ethoxybenzene SCHEMBL365637 | 0.65 | CHRNB2 (0.59) | NLRP3SMN1; SMN2HPGDALDH1A1MAPT | |
| 1-Hydroxy-3-Ethoxybenzene SCHEMBL30597483 | 0.65 | CHRNB2 (0.59) | NLRP3SMN1; SMN2HPGDALDH1A1MAPT | |
| SCHEMBL27582544 | 0.64 | MAPT (0.67) | LMNAMAPK1SMN1; SMN2RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103992245-A | Substituted urea compound and use thereof | UNIV EAST CHINA SCIENCE & TECH | 2014-08-20 | — | — | CN | disclosed |