Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.35 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27911653 | 0.81 | CHRM1 (0.44) | NFKB1 | |
| SCHEMBL9637730 | 0.80 | FOLH1 (0.43) | FOLH1RNPEPENPEPBLMANPEP | |
| SCHEMBL5179485 | 0.79 | CYP1A2 (0.50) | FOLH1MAPTCYP1A2 | |
| SCHEMBL9586717 | 0.74 | RNPEP (0.38) | RNPEPENPEPBLMKDM4EMAPT | |
| SCHEMBL25335004 | 0.73 | — | — | |
| SCHEMBL180035 | 0.72 | RNPEP (0.50) | RNPEPALDH1A1SLC7A5 | |
| SCHEMBL13225821 | 0.71 | ENPEP (0.40) | RNPEPENPEPBLMKDM4EMAPT | |
| SCHEMBL9638452 | 0.71 | FOLH1 (0.47) | FOLH1ENPEPBLMKDM4EMAPT | |
| SCHEMBL7850493 | 0.71 | FOLH1 (0.66) | FOLH1ENPEPANPEPCYP1A2 | |
| SCHEMBL11131728 | 0.70 | TP53 (0.43) | FOLH1RNPEPENPEPSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101657424-B | Dual-action antihypertensive agent | THERAVANCE INC US | 2014-09-24 | — | — | CN | disclosed |