Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.43 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9638452 | 0.85 | FOLH1 (0.47) | FOLH1ENPEPKDM4EMAPTTHRB | |
| SCHEMBL9637611 | 0.83 | FOLH1 (0.48) | FOLH1ENPEPKDM4EMAPTTHRB | |
| SCHEMBL10001330 | 0.83 | ENPEP (0.52) | FOLH1ENPEPANPEPKDM4EMAPT | |
| SCHEMBL9392724 | 0.83 | CHRM1 (0.41) | ENPEPCHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL9637766 | 0.81 | FOLH1 (0.50) | FOLH1ENPEPMAPTCPB2 | |
| SCHEMBL9638476 | 0.81 | FOLH1 (0.50) | FOLH1ENPEPMAPTCPB2 | |
| SCHEMBL9637745 | 0.81 | FOLH1 (0.50) | FOLH1ENPEPMAPTCPB2 | |
| SCHEMBL9637650 | 0.81 | FOLH1 (0.50) | FOLH1ENPEPMAPTCPB2 | |
| SCHEMBL27980396 | 0.80 | FOLH1 (0.36) | FOLH1ENPEPANPEPKDM4EMAPT | |
| SCHEMBL12851375 | 0.78 | GPR84 (0.41) | MAPTBLMCHRM1AKR1A1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367508-B1 | MERCAPTOALKYL ACETOACETATES, USE THEREOF AND A PROCESS FOR THE PREPARATION OF MERCAPTOALKYL ACETOACETATES | ROHM AND HAAS COMPANY (US) | 1992-07-22 | — | — | EP | claimed |
| EP-0367508-A1 | Mercaptoalkyl acetoacetates, use thereof and a process for the preparation of mercaptoalkyl acetoacetates | ROHM AND HAAS COMPANY (US) | 1990-05-09 | — | — | EP | claimed |
| JP-2172965-A | — | — | None | — | — | JP | disclosed |
| EP-0367508-B1 | MERCAPTOALKYL ACETOACETATES, USE THEREOF AND A PROCESS FOR THE PREPARATION OF MERCAPTOALKYL ACETOACETATES | ROHM AND HAAS COMPANY (US) | 1992-07-22 | — | — | EP | disclosed |
| US-4960924-A | Mercaptoalkyl acetoacetates | ROHM AND HAAS COMPANY (US) | 1990-10-02 | — | — | US | disclosed |
| JP-H02172965-A | MERCAPTOALKYL ACETATE | ROHM & HAAS CO | 1990-07-04 | — | — | JP | disclosed |
| EP-0367508-A1 | Mercaptoalkyl acetoacetates, use thereof and a process for the preparation of mercaptoalkyl acetoacetates | ROHM AND HAAS COMPANY (US) | 1990-05-09 | — | — | EP | disclosed |