Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16597351 | 0.82 | LOXL2 (0.50) | ADRB2LOXL2CYP2A6PDPK1CHEK2 | |
| SCHEMBL16610138 | 0.79 | LOXL2 (0.50) | ADRB2LOXL2CYP2A6PDPK1CHEK2 | |
| SCHEMBL13622938 | 0.79 | ADRB2 (0.50) | ADRB2LOXL2CYP2A6PDPK1CHEK2 | |
| SCHEMBL13615828 | 0.75 | ADRB2 (0.46) | ADRB2LOXL2CYP2A6PDPK1CHEK2 | |
| SCHEMBL4355883 | 0.75 | LOXL2 (0.50) | ADRB2LOXL2CYP2A6PDPK1CHEK2 | |
| SCHEMBL27980432 | 0.73 | CYP2A6 (0.44) | ADRB2LOXL2CYP2A6PDPK1CHEK2 | |
| SCHEMBL722198 | 0.71 | PDPK1 (0.77) | ADRB2LOXL2CYP2A6PDPK1CHEK2 | |
| SCHEMBL28790747 | 0.71 | LOXL2 (0.42) | ADRB2LOXL2CYP2A6PDPK1CHEK2 | |
| SCHEMBL23832336 | 0.69 | CYP2A6 (0.55) | ADRB2LOXL2CYP2A6PDPK1CHEK2 | |
| SCHEMBL14814093 | 0.69 | CYP2A6 (0.55) | ADRB2LOXL2CYP2A6PDPK1CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104151381-A | Anti-bacterial activity of 9-HYDROXY derivatives of 6, 11-bicyclolides | ENANTA PHARM INC | 2014-11-19 | — | — | CN | disclosed |
| CN-102088848-B | Antibacterial activity of 6, 11-bicyclic 9-hydroxy derivatives | ENANTA PHARM INC | 2014-07-30 | — | — | CN | disclosed |