Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | CFTR | P13569 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | RORB | Q92753 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28294857 | 0.89 | PTGS1 (0.49) | GAAALDH1A1HSD17B10PTGS1MAPT | |
| SCHEMBL1458185 | 0.87 | GAA (0.60) | GAACFTRALDH1A1HSD17B10PTGS1 | |
| Hydrochloric Acid SCHEMBL2324114 | 0.86 | GAA (0.58) | GAACFTRALDH1A1HSD17B10PTGS1 | |
| SCHEMBL7182044 | 0.82 | GAA (0.55) | GAACFTRALDH1A1HSD17B10PTGS1 | |
| Dimethyl Phthalate SCHEMBL28028655 | 0.79 | GAA (0.66) | GAACFTRALDH1A1HSD17B10MAPT | |
| SCHEMBL653785 | 0.78 | GAA (0.56) | GAACFTRALDH1A1HSD17B10PTGS1 | |
| SCHEMBL4825758 | 0.77 | PTGS1 (0.58) | GAACFTRHSD17B10PTGS1MAPT | |
| SCHEMBL25381631 | 0.76 | CFTR (0.47) | GAACFTRALDH1A1HSD17B10PTGS1 | |
| SCHEMBL29580754 | 0.76 | CFTR (0.49) | GAACFTRALDH1A1HSD17B10PTGS1 | |
| SCHEMBL2796211 | 0.76 | CFTR (0.49) | GAACFTRALDH1A1HSD17B10PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104098503-A | Isoindoline compound, preparation method and anti-depression application thereof | INST MATERIA MEDICA CAMS | 2014-10-15 | — | — | CN | disclosed |