Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29580754 | 1.00 | CFTR (0.49) | CFTRGAAPTGS1MAPTALDH1A1 | |
| SCHEMBL3912237 | 0.86 | LDHA (0.54) | CFTRGAAMAPTALDH1A1HPGD | |
| SCHEMBL2794241 | 0.84 | MCL1 (0.60) | CFTRGAAPTGS1MAPTALDH1A1 | |
| SCHEMBL29530817 | 0.84 | MCL1 (0.60) | CFTRGAAPTGS1MAPTALDH1A1 | |
| SCHEMBL1458185 | 0.84 | GAA (0.60) | CFTRGAAPTGS1MAPTALDH1A1 | |
| SCHEMBL6438400 | 0.83 | GAA (0.54) | CFTRGAAMAPTALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL2324114 | 0.83 | GAA (0.58) | CFTRGAAPTGS1MAPTALDH1A1 | |
| SCHEMBL2798764 | 0.81 | CTSS (0.47) | CFTRPTGS1MCL1KDM4E | |
| SCHEMBL2798768 | 0.81 | CTSS (0.47) | CFTRPTGS1MCL1KDM4E | |
| SCHEMBL9942857 | 0.81 | CFTR (0.71) | CFTRGAAPTGS1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100168079-A1 | Biaryl Benzylamine Derivatives | ANGST DANIELA | 2010-07-01 | — | — | US | disclosed |
| US-20100168079-A1 | Biaryl Benzylamine Derivatives | ANGST DANIELA | 2010-07-01 | — | — | US | disclosed |
| US-20100168079-A1 | Biaryl Benzylamine Derivatives | ANGST DANIELA | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168079-A1 | Biaryl Benzylamine Derivatives | BRD3, BRD2, BBOX1 | CFTR 799/4885GAA 211/4885PTGS1 4198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.