Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2796211 | 1.00 | CFTR (0.49) | CFTRGAAPTGS1MAPTALDH1A1 | |
| SCHEMBL3912237 | 0.86 | LDHA (0.54) | CFTRGAAMAPTALDH1A1HPGD | |
| SCHEMBL2794241 | 0.84 | MCL1 (0.60) | CFTRGAAPTGS1MAPTALDH1A1 | |
| SCHEMBL29530817 | 0.84 | MCL1 (0.60) | CFTRGAAPTGS1MAPTALDH1A1 | |
| SCHEMBL1458185 | 0.84 | GAA (0.60) | CFTRGAAPTGS1MAPTALDH1A1 | |
| SCHEMBL6438400 | 0.83 | GAA (0.54) | CFTRGAAMAPTALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL2324114 | 0.83 | GAA (0.58) | CFTRGAAPTGS1MAPTALDH1A1 | |
| SCHEMBL2798764 | 0.81 | CTSS (0.47) | CFTRPTGS1MCL1KDM4E | |
| SCHEMBL2798768 | 0.81 | CTSS (0.47) | CFTRPTGS1MCL1KDM4E | |
| SCHEMBL9942857 | 0.81 | CFTR (0.71) | CFTRGAAPTGS1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119823106-A | Enhanced nucleic acid polymerization by aromatic compounds | 豪夫迈·罗氏有限公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-114144520-B | Enhanced nucleic acid polymerization by aromatic compounds | 豪夫迈·罗氏有限公司 | 2024-12-13 | — | — | CN | disclosed |
| EP-3994262-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | Stratos Genomics Inc. (US) | 2022-05-11 | — | — | EP | disclosed |