Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | HCAR3 | P49019 | 12/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | MAX | P61244 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17576549 | 0.87 | CASP6 (0.64) | CASP6TSHRHCAR3LMNAMEN1 | |
| SCHEMBL30871388 | 0.87 | CASP6 (0.69) | CASP6TSHRHCAR3LMNA | |
| SCHEMBL7712098 | 0.86 | CASP6 (0.62) | CASP6TSHRHCAR3LMNAMEN1 | |
| SCHEMBL29897190 | 0.82 | CASP6 (0.66) | CASP6TSHRHCAR3LMNA | |
| SCHEMBL19413761 | 0.82 | HCAR3 (0.59) | CASP6TSHRHCAR3LMNA | |
| SCHEMBL18394225 | 0.81 | CASP6 (0.64) | CASP6TSHRHCAR3LMNA | |
| SCHEMBL7706073 | 0.81 | CASP6 (0.55) | CASP6TSHRHCAR3LMNAMEN1 | |
| SCHEMBL4134840 | 0.80 | CASP6 (0.58) | CASP6TSHRHCAR3LMNAMEN1 | |
| SCHEMBL29577830 | 0.79 | CASP6 (1.00) | CASP6TSHRHCAR3LMNA | |
| SCHEMBL504055 | 0.79 | CASP6 (1.00) | CASP6TSHRHCAR3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101970420-B | Oxadiazole derivatives | MERCK SERONO SA | 2014-09-24 | — | — | CN | disclosed |
| CN-102245602-B | Oxadiazole fused heterocyclic derivatives useful for the treatment of multiple sclerosis | MERCK SERONO SA | 2014-09-10 | — | — | CN | disclosed |