Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4362031 | 0.93 | HTR7 (0.41) | HTR7DRD2PRCPATMTDP1 | |
| SCHEMBL28230835 | 0.89 | PARP1 (0.47) | HTR7DRD2PRCPHTR1APARP1 | |
| SCHEMBL27598672 | 0.81 | DRD1 (0.37) | HTR7DRD2PARP1 | |
| SCHEMBL6293516 | 0.77 | PARP1 (0.37) | TDP1PARP1TSHRCYP2A6MAOA | |
| SCHEMBL1836409 | 0.75 | PARP1 (0.35) | HTR7HTR1APARP1CYP2A6MAOA | |
| SCHEMBL12679738 | 0.75 | PDCD1 (0.36) | HTR1APARP1CYP2A6MAOAMAOB | |
| SCHEMBL3281172 | 0.75 | PRCP (0.51) | HTR7DRD2PRCPMAOB | |
| SCHEMBL14278982 | 0.74 | PARP1 (0.44) | HTR7DRD2PARP1 | |
| SCHEMBL31401569 | 0.74 | PARP1 (0.44) | PARP1NPY5R | |
| Hydrochloric Acid SCHEMBL3283120 | 0.73 | PRCP (0.50) | HTR7DRD2PRCPMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102675326-B | Preparation method of 3,4-dihydrobenzene benzopyran [3,4-c] pyrazole tricyclic compound | UNIV EAST CHINA SCIENCE & TECH | 2014-08-20 | — | — | CN | disclosed |