Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SI | P14410 | 2/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11547161 | 0.82 | MGAM (0.44) | MGAMGAASIMGAM2TDP1 | |
| SCHEMBL6444996 | 0.79 | MGAM (0.46) | MGAMGAASIMGAM2 | |
| SCHEMBL5227698 | 0.79 | MGAM (0.46) | MGAMGAASIMGAM2 | |
| SCHEMBL6445001 | 0.79 | MGAM (0.46) | MGAMGAASIMGAM2 | |
| SCHEMBL4876169 | 0.79 | — | — | |
| SCHEMBL4876177 | 0.79 | — | — | |
| SCHEMBL14904413 | 0.79 | — | — | |
| SCHEMBL9068329 | 0.78 | MGAM (0.44) | MGAMGAASIMGAM2 | |
| SCHEMBL28867898 | 0.74 | GAA (0.41) | MGAMGAASIMGAM2TDP1 | |
| SCHEMBL16667687 | 0.74 | MGAM (0.50) | MGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102007118-B | Pyrrolidinone glucokinase activators | HOFFMANN LA ROCHE | 2014-12-31 | — | — | CN | disclosed |