Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | SI | P14410 | 2/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
| ▸ | KDM5C | P41229 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6445001 | 1.00 | MGAM (0.46) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL20528139 | 0.89 | MGAM (0.46) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL5227698 | 0.83 | MGAM (0.46) | MGAMGAASIMGAM2 | |
| SCHEMBL16667687 | 0.82 | MGAM (0.50) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL448049 | 0.81 | ADRA2A (0.41) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL11547161 | 0.81 | MGAM (0.44) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL6865669 | 0.81 | GAA (0.62) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL9068329 | 0.81 | MGAM (0.44) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL2266822 | 0.80 | — | — | |
| SCHEMBL3899433 | 0.80 | TSHR (0.37) | MGAMGAASIMGAM2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053526-A | The chemical synthesis process of one kind (3R, 4S) -4- methylpyrrolidin- 3- carbamate hydrochloride | 南通大学 | 2018-12-21 | — | — | CN | claimed |
| CN-103564405-B | Pear essence and preparation method thereof | GUANGDONG SHUNDA FOOD FLAVORING CO LTD | 2015-01-07 | — | — | CN | claimed |
| CN-103564405-A | Pear essence and preparation method thereof | GUANGDONG SHUNDA FOOD FLAVORING CO LTD | 2014-02-12 | — | — | CN | claimed |
| WO-2023099310-A1 | PREPARATION OF HIGH SOLID CONTENT, SURFACTANT-FREE LATEX USING FUNCTIONAL AMPHIPHILIC WATERBORNE MACRO-RAFT AGENT | BASF SE (DE) | 2023-06-08 | — | — | WO | disclosed |
| EP-3713975-B1 | AN ADDITIVE COMPOSITION AND APPLICATION THEREOF | BASF SE (DE) | 2022-10-12 | — | — | EP | disclosed |
| US-20200369809-A1 | AN ADDITIVE COMPOSITION AND APPLICATION THEREOF | BASF ADVANCED CHEMICALS CO., LTD. (CN) | 2020-11-26 | — | — | US | disclosed |
| US-20200369809-A1 | AN ADDITIVE COMPOSITION AND APPLICATION THEREOF | BASF ADVANCED CHEMICALS CO., LTD. (CN) | 2020-11-26 | — | — | US | disclosed |
| EP-3713975-A1 | AN ADDITIVE COMPOSITION AND APPLICATION THEREOF | BASF SE (DE) | 2020-09-30 | — | — | EP | disclosed |
| CN-111587264-A | Additive composition and application thereof | 巴斯夫欧洲公司 | 2020-08-25 | — | — | CN | disclosed |
| CN-110317191-A | A kind of pyridine-heterocyclic compound and its application as CXCR4 inhibitor | 苏州云轩医药科技有限公司 | 2019-10-11 | — | — | CN | disclosed |
| CN-110167928-A | The quinazoline and derivative that Novel warp benzylamino as SOS1 inhibitor replaces | 勃林格殷格翰国际有限公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-103564405-B | Pear essence and preparation method thereof | GUANGDONG SHUNDA FOOD FLAVORING CO LTD | 2015-01-07 | — | — | CN | disclosed |
| CN-102007118-B | Pyrrolidinone glucokinase activators | HOFFMANN LA ROCHE | 2014-12-31 | — | — | CN | disclosed |
| CN-104080768-A | Aryldihydropyridinones and piperidones as MGAT2 inhibitors | BRISTOL MYERS SQUIBB CO | 2014-10-01 | — | — | CN | disclosed |
| CN-103564405-A | Pear essence and preparation method thereof | GUANGDONG SHUNDA FOOD FLAVORING CO LTD | 2014-02-12 | — | — | CN | disclosed |
| CN-103492377-A | Triazolopyridine compounds as PIM kinase inhibitors | ARRAY BIOPHARMA INC | 2014-01-01 | — | — | CN | disclosed |
| EP-1189874-B1 | EXCITATORY AMINO ACID RECEPTOR MODULATORS | LILLY SA (ES) | 2005-01-26 | — | — | EP | disclosed |
| US-6504052-B1 | 2-carboxycyclopropyl glycine derivatives, used as agonists of glutamate receptors for prophylaxis of psychological and nervous system disorders; anxiolytics; antidepressants; drug abuse; anticonvulsant, analgesic and antiemetic agents | ELI LILLY AND COMPANY | 2003-01-07 | — | — | US | disclosed |
| EP-1189874-A1 | EXCITATORY AMINO ACID RECEPTOR MODULATORS | Lilly, S.A. (ES) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000075102-A1 | EXCITATORY AMINO ACID RECEPTOR MODULATORS | LILLY, S.A. (ES) | 2000-12-14 | — | — | WO | disclosed |