Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SI | P14410 | 2/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28070896 | 0.84 | MGAM (0.41) | MGAMGAASIMGAM2PTGS1 | |
| SCHEMBL27351821 | 0.83 | MGAM (0.50) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL27984239 | 0.82 | MGAM (0.43) | MGAMGAASIMGAM2TDP1 | |
| SCHEMBL27649083 | 0.82 | ADORA3 (0.43) | PTGS1NR1I2PGRADORA3PTGS2 | |
| SCHEMBL28040979 | 0.82 | MGAM (0.43) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL27657768 | 0.82 | MGAM (0.43) | MGAMGAASIMGAM2 | |
| SCHEMBL6445001 | 0.81 | MGAM (0.46) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL5227698 | 0.81 | MGAM (0.46) | MGAMGAASIMGAM2 | |
| SCHEMBL6444996 | 0.81 | MGAM (0.46) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL8961878 | 0.80 | PTGS1 (0.40) | MGAMGAASIMGAM2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4173588-A | FROM 2-METHYL-3-BUTEN-2-OL AND AN ALKYL ACETOACETATE, ORGANOALUMINUM COMPOUND | BASF AKTIENGESELLSCHAFT (DE) | 1979-11-06 | — | — | US | disclosed |