Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27316010 | 0.81 | CFTR (0.40) | ALDH1A1L3MBTL1SMN1; SMN2LMNACFTR | |
| SCHEMBL2604881 | 0.78 | SLC6A2 (0.46) | L3MBTL1SMN1; SMN2LMNAKDM4ECFTR | |
| SCHEMBL29786276 | 0.78 | SLC6A2 (0.46) | L3MBTL1SMN1; SMN2LMNAKDM4ECFTR | |
| SCHEMBL11337414 | 0.76 | CFTR (0.47) | L3MBTL1SMN1; SMN2LMNAKDM4ECFTR | |
| SCHEMBL20098043 | 0.76 | CFTR (0.57) | L3MBTL1SMN1; SMN2KDM4ECFTRSLC6A2 | |
| SCHEMBL24919838 | 0.76 | CFTR (0.47) | L3MBTL1SMN1; SMN2LMNAKDM4ECFTR | |
| SCHEMBL21770565 | 0.76 | CFTR (0.47) | L3MBTL1SMN1; SMN2LMNAKDM4ECFTR | |
| SCHEMBL23689571 | 0.76 | CFTR (0.47) | L3MBTL1SMN1; SMN2LMNAKDM4ECFTR | |
| SCHEMBL3265767 | 0.76 | CYP2A6 (0.47) | L3MBTL1SMN1; SMN2LMNAKDM4ECFTR | |
| SCHEMBL2420685 | 0.75 | SMN1; SMN2 (0.47) | L3MBTL1SMN1; SMN2LMNAKDM4ECFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105705167-A | Bioconjugates of synthetic APELIN polypeptides | 诺华股份有限公司 | 2016-06-22 | — | — | CN | disclosed |
| CN-104220452-A | Synthetic APELIN mimetics for treatment of heart failure | NOVARTIS AG | 2014-12-17 | — | — | CN | disclosed |