Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GRM8 | O00222 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27985096 | 0.81 | ALDH1A1 (0.40) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL27353190 | 0.80 | CA2 (0.41) | CA12CA1CA2CA9 | |
| SCHEMBL30195834 | 0.76 | CYP2A6 (0.47) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL28628804 | 0.76 | CYP2A6 (0.47) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL28628803 | 0.76 | CYP2A6 (0.47) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL24895918 | 0.76 | CYP2A6 (0.47) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL28831206 | 0.74 | CFTR (0.48) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL25005918 | 0.73 | CFTR (0.44) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL30273386 | 0.73 | CFTR (0.44) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL27215799 | 0.73 | CFTR (0.44) | CFTRSLC6A2SLC6A4SLC6A3GOPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1127492-C | Antirheumatic | SHIONOJI & CO LTD (JP) | 2003-11-12 | — | — | CN | disclosed |
| CN-1283194-A | Antirheumatic | SHIONOJI & CO LTD (JP) | 2001-02-07 | — | — | CN | disclosed |
| CN-1035614-C | Benzylidene derivatives | SHIONOGI & CO (JP) | 1997-08-13 | — | — | CN | disclosed |
| CN-1092414-A | Benzylidene derivatives | SHIONOGI & CO (JP) | 1994-09-21 | — | — | CN | disclosed |