Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.75 |
| ▸ | RAB9A | P51151 | 2/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.75 |
| ▸ | MAPT | P10636 | 1/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.75 |
| ▸ | ATM | Q13315 | 1/20 | 0.75 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.75 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.63 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.63 |
| ▸ | MAOB | P27338 | 2/20 | 0.61 |
| ▸ | AR | P10275 | 1/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.60 |
| ▸ | TFEB | P19484 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4019329 | 0.87 | NFE2L2 (0.79) | NPC1RAB9AKDM4EMAPTMAPK1 | |
| SCHEMBL1603719 | 0.87 | NFE2L2 (0.79) | NPC1RAB9AKDM4EMAPTMAPK1 | |
| SCHEMBL7915752 | 0.87 | NFE2L2 (0.79) | NPC1RAB9AKDM4EMAPTMAPK1 | |
| SCHEMBL28360791 | 0.86 | MAPT (1.00) | NPC1RAB9AKDM4EMAPTMAPK1 | |
| SCHEMBL4014094 | 0.85 | CA1 (0.59) | NPC1RAB9AKDM4EMAPTMAPK1 | |
| SCHEMBL108389 | 0.80 | TRPA1 (0.76) | NPC1RAB9AKDM4EMAPTMAPK1 | |
| SCHEMBL717976 | 0.80 | TRPA1 (0.76) | NPC1RAB9AKDM4EMAPTMAPK1 | |
| SCHEMBL16213550 | 0.79 | CYP1A1 (0.67) | KDM4EMAPTTDP1NFE2L2TRPA1 | |
| SCHEMBL633823 | 0.79 | NFE2L2 (0.73) | KDM4EMAPTNFE2L2TRPA1MAOB | |
| SCHEMBL19327368 | 0.79 | NFE2L2 (0.73) | KDM4EMAPTNFE2L2TRPA1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105237411-A | Preparation method for sarpogrelate hydrochloride photodegradable impurity III | SHANDONG QIDU PHARMACEUTICAL | 2016-01-13 | — | — | CN | claimed |
| CN-104356012-A | Preparation method of sarpogrelate hydrochloride photodegradation impurities | SHANDONG QIDU PHARMACEUTICAL | 2015-02-18 | — | — | CN | claimed |
| CN-105237411-A | Preparation method for sarpogrelate hydrochloride photodegradable impurity III | SHANDONG QIDU PHARMACEUTICAL | 2016-01-13 | — | — | CN | disclosed |
| CN-104496769-A | Synthetic method for 2-[2-(3-methoxyphenyl)ethyl]phenol | CHEER FINE PHARMACEUTICAL ANHUI CO LTD | 2015-04-08 | — | — | CN | disclosed |
| CN-104356012-A | Preparation method of sarpogrelate hydrochloride photodegradation impurities | SHANDONG QIDU PHARMACEUTICAL | 2015-02-18 | — | — | CN | disclosed |