SCHEMBL27985408

SCHEMBL27985408

CCc1c(C)c(C)c(C(=O)OC)c(C(=O)OC)c1CC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.45
KDM4E B2RXH2 3/20 0.40
ALDH1A1 P00352 6/20 0.39
HPGD P15428 2/20 0.39
TSHR P16473 2/20 0.39
HSD17B10 Q99714 2/20 0.39
CNR2 P34972 3/20 0.38
NPSR1 Q6W5P4 2/20 0.38
RAB9A P51151 2/20 0.37
NPC1 O15118 1/20 0.37
PKM P14618 1/20 0.37
CNR1 P21554 1/20 0.37
MEN1 O00255 1/20 0.37
MAPT P10636 1/20 0.37
KMT2A Q03164 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C19 P33261 1/20 0.37
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10079108 0.85 LMNA (0.43) LMNAKDM4EALDH1A1HPGDTSHR
SCHEMBL28733590 0.84 LMNA (0.45) LMNAKDM4EALDH1A1HPGDTSHR
SCHEMBL13199247 0.78 ALDH1A1 (0.50) LMNAKDM4EALDH1A1HPGDTSHR
SCHEMBL547214 0.78 KDM4E (0.52) LMNAKDM4EALDH1A1HPGDTSHR
SCHEMBL27985414 0.77 NPC1 (0.42) LMNAKDM4EALDH1A1HPGDCNR2
SCHEMBL27985411 0.76 ALDH1A1 (0.40) LMNAKDM4EALDH1A1HPGDTSHR
SCHEMBL10106030 0.75 KDM4E (0.50) LMNAKDM4EALDH1A1HPGDTSHR
SCHEMBL10165970 0.73 KDM4E (0.52) LMNAKDM4EALDH1A1HPGDTSHR
SCHEMBL1375730 0.72 APP (0.38) LMNAKDM4EALDH1A1HPGDTSHR
SCHEMBL2624814 0.72 KDM4E (0.40) LMNAKDM4EALDH1A1HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104513327-A Olefin polymerization catalyst composition and applications thereof CHINA PETROLEUM & CHEMICAL 2015-04-15 CN claimed
CN-110903418-B Solid catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2021-07-02 CN disclosed
CN-108930072-B Flame-retardant antistatic polypropylene fiber composition and fiber and non-woven fabric prepared from same 中国石油化工股份有限公司 2021-07-02 CN disclosed
CN-110903418-A Solid catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-03-24 CN disclosed
CN-106496374-B A kind of catalyst system being used to prepare olefin polymer and its application 中国石油化工股份有限公司 2019-09-27 CN disclosed
CN-108930072-A Anti-flaming anti-static electricity polypropylene fiber composition and fiber prepared therefrom and non-woven fabrics 中国石油化工股份有限公司 2018-12-04 CN disclosed
CN-107840906-A A kind of ingredient of solid catalyst, catalyst system and pre-polymerized catalyst for olefinic polymerization 中国石油化工股份有限公司 2018-03-27 CN disclosed
CN-107840916-A A kind of ingredient of solid catalyst, catalyst system and pre-polymerized catalyst for olefinic polymerization 中国石油化工股份有限公司 2018-03-27 CN disclosed
CN-105273724-B Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 奇美实业股份有限公司 2017-07-14 CN disclosed
CN-104513329-B Catalyst system and its application for olefinic polymerization 中国石油化工股份有限公司 2017-05-31 CN disclosed
CN-106496366-A A kind of olefin polymerization catalysis and its application 中国石油化工股份有限公司 2017-03-15 CN disclosed
CN-106496374-A A kind of catalyst system and its application for preparing olefin polymer 中国石油化工股份有限公司 2017-03-15 CN disclosed
CN-104513327-B Olefin polymerization catalyst composition and applications thereof 中国石油化工股份有限公司 2017-02-15 CN disclosed
CN-104513329-A Catalyst system used in olefin polymerization and application thereof CHINA PETROLEUM & CHEMICAL 2015-04-15 CN disclosed
CN-104513327-A Olefin polymerization catalyst composition and applications thereof CHINA PETROLEUM & CHEMICAL 2015-04-15 CN disclosed