Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5035148 | 0.78 | CHRM2 (0.42) | — | |
| SCHEMBL20032463 | 0.74 | MAOB (0.41) | MAOBALDH2ALDH3A1 | |
| SCHEMBL8759192 | 0.72 | MAOB (0.43) | MAOBALDH2ALDH3A1 | |
| SCHEMBL3806120 | 0.70 | ALDH1A1 (0.39) | — | |
| SCHEMBL5032752 | 0.70 | ALDH1A1 (0.41) | — | |
| SCHEMBL18982690 | 0.70 | MAOB (0.44) | MAOBALDH2ALDH3A1 | |
| SCHEMBL32672896 | 0.70 | MAOB (0.44) | MAOBALDH2ALDH3A1 | |
| SCHEMBL27444135 | 0.69 | ALDH1A1 (0.50) | — | |
| SCHEMBL6181849 | 0.69 | HDAC3 (0.52) | — | |
| SCHEMBL1013856 | 0.68 | CA2 (0.50) | MAOBALDH2ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104244944-A | Compounds for treating spinal muscular atrophy | PTC THERAPEUTICS INC | 2014-12-24 | — | — | CN | disclosed |