Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31213829 | 1.00 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1MAPTRAB9ANPC1 | |
| SCHEMBL27985685 | 0.86 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1MAPTRAB9ANPC1 | |
| SCHEMBL30132805 | 0.81 | MAPT (0.52) | ALDH1A1L3MBTL1MAPTRAB9ANPC1 | |
| SCHEMBL5787352 | 0.81 | MAPT (0.52) | ALDH1A1L3MBTL1MAPTRAB9ANPC1 | |
| Butane SCHEMBL7723409 | 0.80 | MAPT (0.51) | ALDH1A1L3MBTL1MAPTRAB9ANPC1 | |
| SCHEMBL2107427 | 0.80 | MAPT (0.51) | ALDH1A1L3MBTL1MAPTRAB9ANPC1 | |
| SCHEMBL31213792 | 0.79 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1MAPTRAB9ANPC1 | |
| SCHEMBL1269180 | 0.78 | ALDH1A1 (0.80) | ALDH1A1L3MBTL1MAPTRAB9ANPC1 | |
| SCHEMBL29392267 | 0.78 | ALDH1A1 (0.80) | ALDH1A1L3MBTL1MAPTRAB9ANPC1 | |
| SCHEMBL27856348 | 0.78 | MAPT (0.52) | ALDH1A1L3MBTL1MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102482221-B | bicyclic and tricyclic compounds as KATII inhibitors | PFIZER INC. (US) | 2014-10-22 | — | — | CN | disclosed |