Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.40 |
| ▸ | TLR4 | O00206 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2235300 | 0.89 | TLR4 (0.52) | ACLYTLR4TP53NPC1RAB9A | |
| SCHEMBL2236172 | 0.89 | TLR4 (0.52) | ACLYTLR4TP53NPC1RAB9A | |
| SCHEMBL14108316 | 0.89 | TLR4 (0.52) | ACLYTLR4TP53NPC1RAB9A | |
| SCHEMBL872792 | 0.84 | TLR4 (0.60) | TLR4TP53GAASMN1; SMN2LMNA | |
| SCHEMBL872918 | 0.80 | TLR4 (0.58) | ACLYTLR4TP53GAANPC1 | |
| SCHEMBL28159349 | 0.80 | TLR4 (0.58) | ACLYTLR4TP53GAANPC1 | |
| SCHEMBL3189364 | 0.76 | TLR4 (0.43) | ACLYTLR4TP53GAANPC1 | |
| SCHEMBL2234657 | 0.74 | TLR4 (0.74) | TLR4LMNA | |
| SCHEMBL871856 | 0.74 | TLR4 (0.74) | TLR4LMNA | |
| SCHEMBL2238499 | 0.74 | TLR4 (0.74) | TLR4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101212986-B | Stable emulsified composition | TAKEDA PHARMACEUTICAL | 2015-01-14 | — | — | CN | disclosed |