Acetophenone

Acetophenone

SCHEMBL27986965

CC(=O)c1ccccc1.OCCO

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.60
MAPT P10636 3/20 0.60
LMNA P02545 1/20 0.59
HPGD P15428 3/20 0.54
ALDH1A1 P00352 3/20 0.54
CES1 P23141 5/20 0.52
CES2 O00748 4/20 0.52
KMT2A Q03164 3/20 0.50
MAOB P27338 2/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
TAAR1 Q96RJ0 1/20 0.50
HTT P42858 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
MEN1 O00255 2/20 0.48
KDM4E B2RXH2 1/20 0.48
CYP3A4 P08684 1/20 0.48
ALOX15 P16050 1/20 0.48
MAPK1 P28482 1/20 0.48
TDP1 Q9NUW8 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetophenone SCHEMBL10610347 0.91 SMN1; SMN2 (0.56) SMN1; SMN2MAPTLMNAHPGDALDH1A1
Acetophenone SCHEMBL10397586 0.90 SMN1; SMN2 (0.60) SMN1; SMN2MAPTLMNAHPGDALDH1A1
Acetophenone SCHEMBL27462873 0.89 MAPT (0.71) SMN1; SMN2MAPTLMNAHPGDALDH1A1
Acetophenone SCHEMBL30537000 0.89
Acetophenone SCHEMBL719033 0.89 MAPT (0.71) SMN1; SMN2MAPTLMNAHPGDALDH1A1
Acetophenone SCHEMBL1450855 0.89
Acetophenone SCHEMBL16745259 0.89
Acetophenone SCHEMBL737 0.89
Acetophenone SCHEMBL30537005 0.89
Acetophenone SCHEMBL4356164 0.87 MAPT (0.68) SMN1; SMN2MAPTLMNAHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110300779-A Polyamide-imide resin composition and fluorine-containing coating material 日立化成株式会社 2019-10-01 CN disclosed
CN-104230875-A One-step method for preparing alpha-halogenated acetophenone glycol ketal compound UNIV HUANGSHAN 2014-12-24 CN disclosed
CN-101548241-A Low etching photoresist cleaning agent ANJI MICROELECTRONICS CO LTD (CN) 2009-09-30 CN disclosed