Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.58 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.51 |
| ▸ | CFTR | P13569 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4365379 | 0.87 | ABL1 (0.54) | ABL1MRGPRX4CFTRHTTTMPRSS4 | |
| SCHEMBL28665319 | 0.85 | AR (0.51) | ABL1CFTRRAB9AMAPTHTT | |
| SCHEMBL14995733 | 0.85 | ABL1 (0.60) | ABL1RAB9AMAPTHTTSMN1; SMN2 | |
| SCHEMBL1940800 | 0.81 | CA12 (0.61) | CFTRMAPTSMN1; SMN2KDM4ENOTUM | |
| SCHEMBL2002005 | 0.81 | CFTR (0.69) | MRGPRX4CFTRMAPTCYP2C19KDM4E | |
| SCHEMBL695717 | 0.81 | CFTR (0.51) | CFTRRAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL13948877 | 0.81 | CFTR (0.51) | ABL1CFTRRAB9AMAPTTP53 | |
| SCHEMBL10861732 | 0.81 | NOTUM (0.64) | CFTRMAPTHTTSMN1; SMN2KDM4E | |
| SCHEMBL7779187 | 0.81 | RAB9A (0.50) | RAB9AMAPTHTTTP53SMN1; SMN2 | |
| SCHEMBL31591114 | 0.81 | RAB9A (0.50) | RAB9AMAPTHTTTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100168079-A1 | Biaryl Benzylamine Derivatives | ANGST DANIELA | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168079-A1 | Biaryl Benzylamine Derivatives | BRD3, BRD2, BBOX1 | ABL1 109/4885MRGPRX4 1996/4885CFTR 799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.