Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28235239 | 0.89 | HTT (0.44) | MAPTHTTGAANPC1RAB9A | |
| SCHEMBL27900467 | 0.83 | MAPT (0.50) | MAPTHTTGAANPC1RAB9A | |
| SCHEMBL27703122 | 0.78 | POLB (0.42) | MAPTHTTGAAALDH1A1TP53 | |
| SCHEMBL21089025 | 0.78 | KMT2A (0.37) | MAPTHTTNPC1RAB9AHPGD | |
| SCHEMBL27841531 | 0.78 | CYP1A2 (0.43) | MAPTHTTGAARAB9AHPGD | |
| Hydrochloric Acid SCHEMBL14874807 | 0.78 | LMNA (0.44) | MAPTHTTSCN1ASCN2ASCN3A | |
| SCHEMBL6927717 | 0.76 | KDM1A (0.38) | MAPTHTTGAANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL28207349 | 0.76 | SMN1; SMN2 (0.47) | MAPTHTTGAAHPGDALDH1A1 | |
| SCHEMBL28378687 | 0.74 | MAPT (0.45) | MAPTHTTGAANPC1RAB9A | |
| SCHEMBL29617680 | 0.73 | MAPT (0.52) | MAPTHTTGAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107207983-B | Use of a lubricating composition | 国际壳牌研究有限公司 | 2022-11-18 | — | — | CN | disclosed |
| CN-104220429-A | Non-systemic tgr5 agonists | ARDELYX INC | 2014-12-17 | — | — | CN | disclosed |