Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27988467 | 0.83 | MAPT (0.47) | MAPTHTTGAADHODHNPC1 | |
| SCHEMBL28945254 | 0.83 | GAA (0.49) | MAPTHTTGAAALDH1A1LMNA | |
| SCHEMBL28235239 | 0.80 | HTT (0.44) | MAPTHTTGAADHODHNPC1 | |
| SCHEMBL28378687 | 0.78 | MAPT (0.45) | MAPTHTTGAANPC1RAB9A | |
| SCHEMBL11699661 | 0.77 | ALDH1A1 (0.45) | MAPTHTTGAARAB9AHPGD | |
| SCHEMBL28284685 | 0.77 | HPGD (0.39) | MAPTHTTNPC1RAB9AHPGD | |
| SCHEMBL9702942 | 0.77 | MAPT (0.44) | MAPTHTTGAAALDH1A1LMNA | |
| SCHEMBL29617680 | 0.77 | MAPT (0.52) | MAPTHTTGAANPC1RAB9A | |
| SCHEMBL8984386 | 0.77 | MAPT (0.52) | MAPTHTTGAANPC1RAB9A | |
| SCHEMBL29607224 | 0.76 | ALDH1A1 (0.51) | MAPTHTTGAADHODHNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103260584-A | Dye composition having low content of ammonia | OREAL | 2013-08-21 | — | — | CN | disclosed |
| CN-102821738-A | Hair treatment process using a direct emulsion comprising an oxidizing agent and a direct emulsion containing an alkaline agent | OREAL | 2012-12-12 | — | — | CN | disclosed |