Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.45 |
| ▸ | ABAT | P80404 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1581489 | 0.88 | GPR35 (0.60) | ALDH1A1MAPK1GPR35TP53HPGD | |
| SCHEMBL6186809 | 0.88 | GPR35 (0.49) | ALDH1A1MAPK1GPR35TP53HPGD | |
| SCHEMBL1602832 | 0.84 | MAPK1 (0.51) | ALDH1A1MAPK1GPR35TP53HPGD | |
| SCHEMBL10509625 | 0.78 | TSHR (0.50) | ALDH1A1MAPK1TSHRCA1CA2 | |
| SCHEMBL27657684 | 0.78 | EGFR (0.46) | ALDH1A1MAPK1GPR35TP53HPGD | |
| SCHEMBL7008104 | 0.78 | MEN1 (0.52) | ALDH1A1TSHRSMN1; SMN2KDM4EMAPT | |
| SCHEMBL15467486 | 0.78 | MAPK1 (0.45) | ALDH1A1MAPK1GPR35TP53HPGD | |
| SCHEMBL4847049 | 0.76 | GPR35 (0.58) | ALDH1A1MAPK1GPR35TP53HPGD | |
| SCHEMBL28760190 | 0.76 | POLB (0.49) | ALDH1A1MAPK1GPR35TP53HPGD | |
| SCHEMBL7005240 | 0.76 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2L3MBTL1ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104230935-A | Anti-tumor effect and application of compound containing alicyclic structure | LIAONING LIFENG TECHNOLOGY DEV CO LTD | 2014-12-24 | — | — | CN | disclosed |
| CN-102241678-B | Anti-tumor effect and application of alicyclic structure-containing compound | LIAONING LIFENG SCIENTIFIC & TECHNOLOGY DEVELOPMENT Co.,Ltd. (CN) | 2014-10-29 | — | — | CN | disclosed |