Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22518704 | 0.82 | L3MBTL1 (0.45) | L3MBTL1SCN9APOLBMAPK1CYP1A2 | |
| SCHEMBL12301395 | 0.82 | L3MBTL1 (0.45) | L3MBTL1SCN9APOLBMAPK1CYP1A2 | |
| SCHEMBL20469353 | 0.79 | L3MBTL1 (0.42) | L3MBTL1SCN9APOLBMAPK1CYP1A2 | |
| SCHEMBL31508041 | 0.78 | L3MBTL1 (0.45) | L3MBTL1POLBMAPK1CYP1A2SMN1; SMN2 | |
| SCHEMBL22518710 | 0.78 | L3MBTL1 (0.45) | L3MBTL1POLBMAPK1CYP1A2SMN1; SMN2 | |
| SCHEMBL29005123 | 0.78 | L3MBTL1 (0.45) | L3MBTL1SCN9APOLBMAPK1CYP1A2 | |
| SCHEMBL28013297 | 0.78 | L3MBTL1 (0.45) | L3MBTL1POLBMAPK1CYP1A2SMN1; SMN2 | |
| SCHEMBL29005174 | 0.77 | L3MBTL1 (0.41) | L3MBTL1SCN9APOLBMAPK1CYP1A2 | |
| SCHEMBL27988925 | 0.77 | L3MBTL1 (0.45) | L3MBTL1CYP1A2SMN1; SMN2TSHRMAPT | |
| SCHEMBL30302222 | 0.77 | SIRT6 (0.41) | SIRT6SMN1; SMN2TSHRMAPTPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104203928-A | Triazinone compound and T-type calcium channel inhibitor | NISSAN CHEMICAL IND LTD | 2014-12-10 | — | — | CN | disclosed |