Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.51 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PDE2A | O00408 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27989284 | 0.95 | LMNA (0.55) | KDM4ELMNASMN1; SMN2HPGDPLAU | |
| SCHEMBL3899897 | 0.89 | PLAU (0.54) | KDM4ELMNASMN1; SMN2HPGDPLAU | |
| SCHEMBL6380001 | 0.84 | TRPV1 (0.63) | HPGDPLAU | |
| SCHEMBL6376195 | 0.83 | NPC1 (0.59) | SMN1; SMN2HPGDPLAUMEN1KMT2A | |
| SCHEMBL7372649 | 0.82 | CYP3A4 (0.63) | KDM4EPLAUMEN1KMT2AL3MBTL1 | |
| SCHEMBL31349283 | 0.81 | MEN1 (0.56) | KDM4EMEN1KMT2A | |
| Benzyl Benzylcarbamate SCHEMBL1136818 | 0.81 | PLAU (0.70) | LMNASMN1; SMN2PLAU | |
| SCHEMBL7647107 | 0.80 | NPC1 (0.59) | SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL7373867 | 0.80 | CYP3A4 (0.55) | SMN1; SMN2HPGDPLAUMEN1KMT2A | |
| SCHEMBL17864888 | 0.79 | LMNA (0.61) | LMNASMN1; SMN2PLAUL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679239-B | Inhibitors of histone deacetylase | METHYLGENE INC | 2014-12-10 | — | — | CN | disclosed |