SCHEMBL2799113

SCHEMBL2799113

O=c1ccc2c(OC/C=C/c3ccccc3)c3ccoc3cc2o1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 15/20 0.63
KCNA5 P22460 12/20 0.63
ALDH1A1 P00352 5/20 0.63
KCNA1 Q09470 3/20 0.63
KCNA4 P22459 2/20 0.63
LMNA P02545 2/20 0.63
CYP1B1 Q16678 2/20 0.63
KCNA2 P16389 2/20 0.63
THRB P10828 2/20 0.63
ACHE P22303 1/20 0.63
KCNN4 O15554 1/20 0.63
KCNA6 P17658 1/20 0.63
KCNMA1 Q12791 1/20 0.63
KCNH2 Q12809 1/20 0.63
KCNN1 Q92952 1/20 0.63
KCNA7 Q96RP8 1/20 0.63
KCNN2 Q9H2S1 1/20 0.63
CYP3A4 P08684 4/20 0.60
KDM4E B2RXH2 4/20 0.60
CYP2D6 P10635 3/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2799121 1.00 KCNA3 (0.63) KCNA3KCNA5ALDH1A1KCNA1KCNA4
SCHEMBL2800519 0.79 KCNA3 (0.80) KCNA3KCNA5ALDH1A1KCNA1KCNA4
SCHEMBL2585454 0.77 KCNA3 (1.00) KCNA3KCNA5ALDH1A1KCNA1KCNA4
SCHEMBL2583446 0.77 KCNA3 (1.00) KCNA3KCNA5ALDH1A1KCNA1KCNA4
SCHEMBL29410610 0.77 KCNA3 (1.00) KCNA3KCNA5ALDH1A1KCNA1KCNA4
SCHEMBL2798087 0.77 KCNA3 (0.86) KCNA3KCNA5ALDH1A1KCNA1KCNA4
Isoimperatorin SCHEMBL15090959 0.77 ALDH1A1 (1.00) KCNA3KCNA5ALDH1A1LMNACYP1B1
SCHEMBL2585444 0.76 KCNA3 (1.00) KCNA3KCNA5ALDH1A1KCNA1KCNA4
SCHEMBL2801814 0.76 KCNA3 (0.93) KCNA3KCNA5ALDH1A1KCNA1KCNA4
SCHEMBL9122678 0.76 ALDH1A1 (0.71) KCNA3KCNA5ALDH1A1KCNA1KCNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7772408-B1 Substituted 5-alkoxypsoralens as inhibitors of potassium channel activity in lymphocytes and other cells THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-08-10 US claimed
WO-2025082731-A1 INTRANASAL FORMULATIONS FOR TREATING OBSTRUCTIVE SLEEP APNEA MOSANNA THERAPEUTICS AG (CH) 2025-04-24 WO disclosed
US-7772408-B1 Substituted 5-alkoxypsoralens as inhibitors of potassium channel activity in lymphocytes and other cells THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-08-10 US disclosed
US-7772408-B1 Substituted 5-alkoxypsoralens as inhibitors of potassium channel activity in lymphocytes and other cells THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-08-10 US disclosed
US-7772408-B1 Substituted 5-alkoxypsoralens as inhibitors of potassium channel activity in lymphocytes and other cells THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-08-10 US disclosed