Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15135573 | 0.92 | LMNA (0.43) | MCL1RXFP1LMNAMETAP2MEN1 | |
| SCHEMBL28794429 | 0.88 | MCL1 (0.49) | MCL1RXFP1EPRS1 | |
| SCHEMBL27662263 | 0.81 | TP53 (0.41) | LMNAMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL2631442 | 0.79 | NPC1 (0.38) | MCL1RXFP1XDHLMNAMETAP2 | |
| SCHEMBL858475 | 0.79 | HTT (0.53) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15135518 | 0.79 | TUBB4A (0.51) | LMNASMN1; SMN2 | |
| SCHEMBL15135533 | 0.76 | AKR1B1 (0.50) | LMNAMEN1KMT2ARAB9AMAPT | |
| SCHEMBL15135658 | 0.75 | NPC1 (0.51) | LMNAMETAP2MEN1KMT2ANPC1 | |
| SCHEMBL15135555 | 0.75 | NPC1 (0.51) | RXFP1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL15135444 | 0.75 | MAP4K4 (0.43) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102875473-B | Preparation method of replaced-2-carbonyl imidazole compound | UNIV ZHEJIANG | 2014-11-26 | — | — | CN | disclosed |