Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | GFER | P55789 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4254928 | 0.87 | MAPT (0.65) | MAPTALDH1A1KMT2AKDM4ELMNA | |
| Hydrochloric Acid SCHEMBL4249730 | 0.86 | MAPT (0.67) | MAPTALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL6806983 | 0.85 | L3MBTL1 (0.68) | MAPTALDH1A1KMT2AKDM4ELMNA | |
| Hydrochloric Acid SCHEMBL14876546 | 0.84 | L3MBTL1 (0.66) | MAPTALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL4223235 | 0.83 | ABCB1 (0.67) | MAPTALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL4223307 | 0.82 | ABCB1 (0.69) | MAPTALDH1A1KMT2AKDM4ELMNA | |
| Hydrochloric Acid SCHEMBL4220525 | 0.82 | ABCB1 (0.65) | MAPTALDH1A1KMT2AKDM4ELMNA | |
| Hydrochloric Acid SCHEMBL4220020 | 0.82 | ABCB1 (0.65) | MAPTALDH1A1KMT2AKDM4ELMNA | |
| Hydrochloric Acid SCHEMBL4223003 | 0.81 | ABCB1 (0.67) | MAPTALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL25568846 | 0.80 | ABCB1 (0.80) | MAPTKMT2AKDM4EABCB1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10828281-B2 | Non-hydrophobic compounds for use in treating metastasis and/or cartilage defect | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2020-11-10 | — | — | US | disclosed |
| US-20100168150-A1 | Camptothecin Analogue Compounds, a Process for Their Preparation and Pharmaceutical Compositions Containing Them. | LES LABORATOIRES SERVIER (FR) | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168150-A1 | Camptothecin Analogue Compounds, a Process for Their Preparation and Pharmaceutical Compositions Containing Them. | ALK, TOP1, CGAS | MAPT 3543/4885ALDH1A1 755/4885KMT2A 3026/4885 |
| US-10828281-B2 | Non-hydrophobic compounds for use in treating metastasis and/or cartilage defect | VIM, MATR3, TP53 | MAPT 168/4885ALDH1A1 1636/4885KMT2A 4613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.