Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | GFER | P55789 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4249730 | 0.99 | MAPT (0.67) | MAPTALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL4223235 | 0.93 | ABCB1 (0.67) | MAPTALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL4223307 | 0.92 | ABCB1 (0.69) | MAPTALDH1A1KMT2AKDM4ELMNA | |
| Hydrochloric Acid SCHEMBL4220525 | 0.92 | ABCB1 (0.65) | MAPTALDH1A1KMT2AKDM4ELMNA | |
| Hydrochloric Acid SCHEMBL4220020 | 0.92 | ABCB1 (0.65) | MAPTALDH1A1KMT2AKDM4ELMNA | |
| Hydrochloric Acid SCHEMBL4223003 | 0.91 | ABCB1 (0.67) | MAPTALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL2799283 | 0.87 | MAPT (0.66) | MAPTALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL5456103 | 0.86 | L3MBTL1 (0.66) | MAPTALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL31109170 | 0.81 | ABCB1 (0.67) | ABCB1DHCR7ABCG2 | |
| SCHEMBL5456104 | 0.81 | ABCB1 (0.68) | MAPTALDH1A1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090088450-A1 | 5-ht7 receptor antagonists | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088450-A1 | 5-ht7 receptor antagonists | HTR7, HTR1A, HTR5A | MAPT 1567/4885ALDH1A1 3390/4885KMT2A 2533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.