Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4611702 | 0.84 | PSIP1 (0.41) | PSIP1CA2BACE1KDM4EDDR1 | |
| SCHEMBL15358096 | 0.81 | PSIP1 (0.40) | PSIP1CA2CA1CA9DDR1 | |
| SCHEMBL2853707 | 0.81 | GAA (0.46) | PSIP1CA2CA1CA9CA12 | |
| Hydrochloric Acid SCHEMBL1017372 | 0.80 | PSIP1 (0.39) | PSIP1CA2CA1CA9DDR1 | |
| SCHEMBL16541866 | 0.80 | DDR1 (0.44) | PSIP1SMN1; SMN2DDR1 | |
| SCHEMBL12997839 | 0.80 | DDR1 (0.54) | DDR1 | |
| Hydrochloric Acid SCHEMBL1262779 | 0.79 | DDR1 (0.52) | DDR1 | |
| Hydrochloric Acid SCHEMBL16528214 | 0.79 | DDR1 (0.43) | PSIP1SMN1; SMN2DDR1GAA | |
| Hydrochloric Acid SCHEMBL1016622 | 0.79 | DDR1 (0.44) | PSIP1KDM4ESMN1; SMN2DDR1GAA | |
| SCHEMBL28682608 | 0.78 | CA1 (0.42) | PSIP1CA2CA1CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104379568-A | Quinazolinedione derivative | CHUGAI PHARMACEUTICAL CO LTD | 2015-02-25 | — | — | CN | disclosed |