Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27993121 | 0.84 | PSIP1 (0.53) | PSIP1CA2KDM4EDDR1BACE1 | |
| SCHEMBL15358096 | 0.77 | PSIP1 (0.40) | PSIP1CA2LMNADDR1SLC6A4 | |
| Trifluoroacetic Acid SCHEMBL4613399 | 0.77 | DDR1 (0.40) | DDR1 | |
| Hydrochloric Acid SCHEMBL1017372 | 0.76 | PSIP1 (0.39) | PSIP1CA2LMNADDR1SLC6A4 | |
| SCHEMBL2853707 | 0.74 | GAA (0.46) | PSIP1CA2KDM4EMAPK1DDR1 | |
| SCHEMBL4683962 | 0.73 | CA2 (0.50) | CA2KDM4ELMNAPOLBMAPK1 | |
| SCHEMBL12997839 | 0.72 | DDR1 (0.54) | DDR1 | |
| SCHEMBL28247232 | 0.72 | MMP2 (0.41) | PSIP1CA2ALDH1A1 | |
| SCHEMBL27495350 | 0.72 | CA2 (0.46) | CA2KDM4ELMNAPOLBMAPK1 | |
| SCHEMBL16541866 | 0.72 | DDR1 (0.44) | PSIP1DDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910298-A2 | PHENYLGLYCINAMIDE AND PYRIDYLGLYCINAMIDE DERIVATIVES USEFUL AS ANTICOAGULANTS | Brystol-Myers Squibb Company (US) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007002313-A2 | PHENYLGLYCINAMIDE AND PYRIDYLGLYCINAMIDE DERIVATIVES USEFUL AS ANTICOAGULANTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-01-04 | — | — | WO | disclosed |