Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HTR1F | P30939 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27993161 | 0.86 | PGK1 (0.45) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL27993164 | 0.80 | KMT2A (0.58) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL27993499 | 0.79 | CYP1A2 (0.49) | LMNAALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27993155 | 0.79 | CYP1A2 (0.51) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL11651996 | 0.77 | PGK1 (0.50) | MAPT | |
| SCHEMBL5743844 | 0.73 | PGK1 (0.49) | KMT2AMAPTLMNAALDH1A1POLB | |
| SCHEMBL27993563 | 0.73 | CYP3A4 (0.46) | MEN1KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL27986798 | 0.73 | MEN1 (0.42) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL14319835 | 0.71 | MEN1 (1.00) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL5234546 | 0.71 | KCNMA1 (0.44) | MEN1KMT2AMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104163791-A | N-pyridine (hetero) aryl amide compound and preparation method and application thereof | HUNAN RES INST CHEMICAL IND | 2014-11-26 | — | — | CN | claimed |
| CN-104163791-A | N-pyridine (hetero) aryl amide compound and preparation method and application thereof | HUNAN RES INST CHEMICAL IND | 2014-11-26 | — | — | CN | disclosed |