SCHEMBL27993233

SCHEMBL27993233

C=C(C)C(N)=O.C=CC(=O)NCC

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.48
TSHR P16473 4/20 0.46
ALDH1A1 P00352 4/20 0.46
MAPK1 P28482 1/20 0.46
ZDHHC20 Q5W0Z9 1/20 0.44
ZDHHC2 Q9UIJ5 1/20 0.44
FGFR4 P22455 1/20 0.33
TGM2 P21980 1/20 0.33
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP3 P08254 1/20 0.30
MMP9 P14780 1/20 0.30
MMP8 P22894 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28097224 0.87 TDP1 (0.36) TDP1TSHRALDH1A1MAPK1ZDHHC20
Methacrylic Acid SCHEMBL31155475 0.86 ALDH1A1 (0.54) TDP1TSHRALDH1A1MAPK1ZDHHC20
SCHEMBL8037505 0.86 ALDH1A1 (0.67) TDP1TSHRALDH1A1MAPK1ZDHHC20
SCHEMBL9238864 0.86 TDP1 (0.50) TDP1TSHRALDH1A1MAPK1ZDHHC20
Acrylamide SCHEMBL27874504 0.85 ALDH1A1 (0.52) TDP1TSHRALDH1A1MAPK1ZDHHC20
Acetone SCHEMBL28395964 0.85 ALDH1A1 (0.56) TDP1TSHRALDH1A1MAPK1ZDHHC20
SCHEMBL17047583 0.85 TSHR (0.62) TDP1TSHRALDH1A1MAPK1ZDHHC20
SCHEMBL15005 0.85
SCHEMBL28072650 0.85 ZDHHC20 (0.55) TDP1TSHRALDH1A1MAPK1ZDHHC20
SCHEMBL28231033 0.85 ZDHHC20 (0.55) TDP1TSHRALDH1A1MAPK1ZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102811701-B Composition, combination and method for making up eyelashes or eyebrows L'OREAL (FR) 2016-01-20 CN disclosed
CN-104427967-A Method for forming a coloured pattern on keratin fibres using a composition comprising a hydrophobic film-forming polymer, at least one volatile solvent and at least one pigment OREAL 2015-03-18 CN disclosed
CN-104379115-A Double-coating method for dyeing keratin fibers OREAL 2015-02-25 CN disclosed