Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.51 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.49 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.39 |
| ▸ | PARP11 | Q9NR21 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31504068 | 0.87 | GRIA1 (0.56) | CD274GRIA1CACNG8HTR1AHTR7 | |
| SCHEMBL28119371 | 0.81 | PARP1 (0.43) | TRPA1ADORA1PDK2NISCHPARP10 | |
| SCHEMBL10922053 | 0.80 | CHEK1 (0.50) | CD274HTR7ADORA1PDK2USP2 | |
| SCHEMBL4718616 | 0.78 | KDM4E (0.63) | NISCHPARP10PARP11KDM4EMEN1 | |
| SCHEMBL8154134 | 0.77 | PARP11 (0.68) | CD274GRIA1CACNG8PARP10PARP11 | |
| SCHEMBL7743680 | 0.76 | CD274 (0.72) | CD274GRIA1CACNG8 | |
| SCHEMBL23785442 | 0.76 | PARP10 (0.44) | PARP10PARP11KDM4EMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL7746004 | 0.75 | CD274 (0.71) | CD274GRIA1CACNG8 | |
| SCHEMBL10920456 | 0.75 | ALDH1A1 (0.50) | ADORA1PARP10PARP11KDM4EMEN1 | |
| SCHEMBL17785717 | 0.74 | JAK2 (0.41) | CD274PARP10PARP11SMN1; SMN2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104204136-B | Indolo [2,1-a ] quinazoline derivatives for stabilizing organic materials | 巴斯夫欧洲公司 | 2016-12-28 | — | — | CN | disclosed |
| CN-104204136-A | Indolo [2,1-a ] quinazoline derivatives for stabilizing organic materials | BASF SE | 2014-12-10 | — | — | CN | disclosed |