Acrylic Acid

Acrylic Acid

SCHEMBL27993445

C=C(C)C(=O)OCCCCC#N.C=CC(=O)O

nearest known ligand 0.50

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Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.50
POLB P06746 1/20 0.43
APEX1 P27695 1/20 0.43
HTT P42858 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
THRB P10828 1/20 0.40
ALDH1A1 P00352 3/20 0.37
CYP3A4 P08684 1/20 0.37
HPGD P15428 1/20 0.34
ZDHHC20 Q5W0Z9 1/20 0.32
HCAR2 Q8TDS4 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
LMNA P02545 1/20 0.30
DNM1 Q05193 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL528601 0.91 TSHR (0.59) TSHRPOLBAPEX1HTTTDP1
Acrylic Acid SCHEMBL28829432 0.89 THRB (0.43) TSHRPOLBAPEX1HTTTDP1
SCHEMBL10409035 0.89 TSHR (0.62) TSHRPOLBAPEX1HTTTDP1
SCHEMBL7061249 0.89 TSHR (0.62) TSHRPOLBAPEX1HTTTDP1
SCHEMBL11774726 0.89 TSHR (0.62) TSHRPOLBAPEX1HTTTDP1
SCHEMBL530161 0.85 TSHR (0.56) TSHRPOLBAPEX1HTTTDP1
Methacrylic Acid SCHEMBL27993447 0.82 TSHR (0.53) TSHRPOLBAPEX1HTTTDP1
Acrylic Acid SCHEMBL10347502 0.81 TSHR (0.77) TSHRPOLBAPEX1HTTTDP1
Acrylic Acid SCHEMBL4378304 0.81 TSHR (0.56) TSHRPOLBAPEX1HTTTDP1
Acrylic Acid SCHEMBL2693137 0.80 THRB (0.59) TSHRPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107406630-B Nitrile rubber composition and rubber crosslinked product 日本瑞翁株式会社 2019-12-03 CN disclosed
CN-110461892-A Nitrile group-containing copolymer rubber ZEON CORP 2019-11-15 CN disclosed
CN-110431157-A The manufacturing method of the nitrile rubber containing carboxyl ZEON CORP 2019-11-08 CN disclosed
CN-110431184-A Bridging property rubber composition and rubber cross object ZEON CORP 2019-11-08 CN disclosed
CN-110402259-A Nitrile group-containing copolymer rubber ZEON CORP 2019-11-01 CN disclosed
CN-110352217-A Nitrile group-containing copolymer rubber and crosslinked nitrile group-containing copolymer rubber 日本瑞翁株式会社 2019-10-18 CN disclosed
CN-107001715-B Nitrile rubber composition, latex composition of highly saturated nitrile rubber, and rubber crosslinked product 日本瑞翁株式会社 2019-08-13 CN disclosed
CN-110088154-A Nitrile rubber containing carboxyl and its manufacturing method, Cross-linkable nitrile rubber composition and rubber cross object 日本瑞翁株式会社 2019-08-02 CN disclosed
CN-107075182-B Rubber cross object 日本瑞翁株式会社 2019-03-19 CN disclosed
CN-107108764-B The manufacturing method of high saturation nitrile rubber 日本瑞翁株式会社 2019-03-19 CN disclosed
CN-104870546-B Rubber composition and formed body 日本瑞翁株式会社 2017-06-13 CN disclosed
CN-106536580-A Nitrile-group-containing copolymer rubber, crosslinkable rubber composition, and crosslinked rubber 日本瑞翁株式会社 2017-03-22 CN disclosed
CN-106536570-A Method for producing amino group-containing polymers using heterogeneous iron catalysts 阿朗新科德国有限责任公司 2017-03-22 CN disclosed
CN-105934474-A Cross-linkable nitrile rubber composition and cross-linked rubber 日本瑞翁株式会社 2016-09-07 CN disclosed
CN-104583298-B Bridging property rubber composition and rubber cross thing 日本瑞翁株式会社 2016-08-17 CN disclosed
CN-105555809-A Nitrile copolymer rubber and production method for same ZEON CORP 2016-05-04 CN disclosed
CN-104870546-A Rubber composition and molded article ZEON CORP 2015-08-26 CN disclosed
CN-104583298-A Crosslinkable rubber composition and crosslinked rubber ZEON CORP 2015-04-29 CN disclosed
CN-104428325-A Hydrogenation of diene-based polymer latex UNIV WATERLOO 2015-03-18 CN disclosed
CN-104379614-A Tandem metathesis and hydrogenation of diene-based polymers in latex UNIV WATERLOO 2015-02-25 CN disclosed