Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | PRKACG | P22612 | 1/20 | 0.33 |
| ▸ | PRKACB | P22694 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 6/20 | 0.32 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11651293 | 0.75 | ALDH1A1 (0.56) | MEN1KMT2AKDM4EUSP2ALDH1A1 | |
| SCHEMBL27994997 | 0.68 | TACR1 (0.36) | MEN1KMT2AALDH1A1GAA | |
| SCHEMBL11210965 | 0.68 | MAPT (0.64) | MEN1KMT2AKDM4EUSP2ALDH1A1 | |
| SCHEMBL8496241 | 0.68 | GAA (0.51) | MEN1KMT2AKDM4EUSP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8494025 | 0.66 | GAA (0.54) | MEN1KMT2AKDM4EUSP2ALDH1A1 | |
| SCHEMBL14839501 | 0.66 | KDM4E (0.38) | KDM4EALDH1A1GAAMAPTHTT | |
| SCHEMBL14833093 | 0.66 | HTR2C (0.50) | MAPTHTR2CHTR2B | |
| Morpholine SCHEMBL25275052 | 0.65 | MPO (0.40) | KDM4EUSP2ALDH1A1MPO | |
| SCHEMBL25272789 | 0.65 | PRKACA (0.41) | PRKACAPRKACGPRKACBMPO | |
| SCHEMBL7290782 | 0.64 | TSHR (0.40) | MEN1KMT2AKDM4EGAAHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104230823-A | Preparation method for gefitinib | CHONGQING SHENGHUAXI PHARMA CO | 2014-12-24 | — | — | CN | disclosed |