Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 8/20 | 0.56 |
| ▸ | THRA | P10827 | 6/20 | 0.56 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31536946 | 0.79 | THRB (0.72) | THRBTHRAPTGS2PPARAPPARG | |
| SCHEMBL27545394 | 0.79 | THRB (0.48) | THRBTHRATSHRMEN1KMT2A | |
| SCHEMBL29690339 | 0.78 | THRB (0.63) | THRBTHRAPPARAPPARGMEN1 | |
| SCHEMBL29046993 | 0.77 | THRB (0.46) | THRBTHRANCEH1HPGDTSHR | |
| SCHEMBL2466995 | 0.77 | THRB (0.89) | THRBTHRAHPGDTSHRPTGS2 | |
| SCHEMBL10426036 | 0.77 | THRA (0.37) | THRBTHRAHPGDKDM4EMEN1 | |
| SCHEMBL8836156 | 0.75 | THRB (0.50) | THRBTHRANCEH1TYMS | |
| SCHEMBL27748618 | 0.75 | THRB (0.59) | THRBTHRANCEH1HPGDTYMS | |
| SCHEMBL1375932 | 0.74 | THRB (0.39) | THRBTHRAHPGDTSHRKDM4E | |
| SCHEMBL4371724 | 0.74 | CA12 (0.40) | THRBTHRAHPGDTSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104254578-A | Substrates in powder or fiber form | DOW CORNING | 2014-12-31 | — | — | CN | disclosed |