Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.35 |
| ▸ | NAALAD2 | Q9Y3Q0 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394607 | 0.83 | FOLH1 (0.42) | FOLH1NAALAD2ALDH1A1MEN1LMNA | |
| SCHEMBL24966082 | 0.83 | FOLH1 (0.42) | FOLH1NAALAD2ALDH1A1MEN1LMNA | |
| SCHEMBL7394606 | 0.83 | FOLH1 (0.42) | FOLH1NAALAD2ALDH1A1MEN1LMNA | |
| SCHEMBL29657364 | 0.80 | ALDH1A1 (0.43) | FOLH1NAALAD2ALDH1A1MEN1LMNA | |
| SCHEMBL882883 | 0.80 | ALDH1A1 (0.43) | FOLH1NAALAD2ALDH1A1MEN1LMNA | |
| SCHEMBL21635774 | 0.80 | ALDH1A1 (0.43) | FOLH1NAALAD2ALDH1A1MEN1LMNA | |
| SCHEMBL160128 | 0.78 | — | — | |
| SCHEMBL28986122 | 0.78 | ACE2 (0.38) | ACE2ALDH1A1ACECHRM1AKR1A1 | |
| SCHEMBL5728555 | 0.78 | — | — | |
| SCHEMBL722207 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104244932-A | Inhibitors of arginase and their therapeutic applications | MARS INC | 2014-12-24 | — | — | CN | disclosed |