Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.42 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.35 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394607 | 1.00 | FOLH1 (0.42) | FOLH1NAALAD2ALDH1A1MEN1LMNA | |
| SCHEMBL24966082 | 1.00 | FOLH1 (0.42) | FOLH1NAALAD2ALDH1A1MEN1LMNA | |
| SCHEMBL7561576 | 0.84 | FOLH1 (0.41) | FOLH1NAALAD2ALDH1A1MEN1LMNA | |
| Hydrochloric Acid SCHEMBL19949198 | 0.84 | CHRM1 (0.40) | FOLH1NAALAD2ALDH1A1MEN1LMNA | |
| Hydrochloric Acid SCHEMBL19949047 | 0.83 | ALDH1A1 (0.48) | FOLH1NAALAD2ALDH1A1MEN1LMNA | |
| SCHEMBL28251227 | 0.83 | FOLH1 (0.39) | FOLH1NAALAD2ALDH1A1MEN1LMNA | |
| SCHEMBL27995355 | 0.83 | ACE2 (0.37) | FOLH1NAALAD2ALDH1A1MEN1LMNA | |
| SCHEMBL27139876 | 0.82 | FOLH1 (0.38) | FOLH1NAALAD2ALDH1A1MEN1LMNA | |
| SCHEMBL27139873 | 0.82 | FOLH1 (0.38) | FOLH1NAALAD2ALDH1A1MEN1LMNA | |
| SCHEMBL16442209 | 0.82 | KISS1R (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458781-B1 | BLOCKERS CALCIUM CHANNEL ANTAGONISTS FOR STROKES, BRAIN DISORDERS | WARNER-LAMBERT COMPANY | 2002-10-01 | — | — | US | claimed |
| WO-1999055688-A1 | SUBSTITUTED DIARYLALKYL AMIDES AS CALCIUM CHANNEL ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1999-11-04 | — | — | WO | claimed |
| US-6458781-B1 | BLOCKERS CALCIUM CHANNEL ANTAGONISTS FOR STROKES, BRAIN DISORDERS | WARNER-LAMBERT COMPANY | 2002-10-01 | — | — | US | disclosed |
| WO-1999055688-A1 | SUBSTITUTED DIARYLALKYL AMIDES AS CALCIUM CHANNEL ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1999-11-04 | — | — | WO | disclosed |