SCHEMBL27995366

SCHEMBL27995366

Cc1cc(O[SH](=O)=O)cc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 7/20 0.50
CYP2A6 P11509 4/20 0.50
ALDH1A1 P00352 5/20 0.41
HSD17B10 Q99714 2/20 0.37
HPGD P15428 1/20 0.37
KDM4E B2RXH2 1/20 0.37
GAA P10253 1/20 0.37
KMT2A Q03164 1/20 0.36
CDC25B P30305 1/20 0.35
MAPT P10636 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
TSHR P16473 1/20 0.34
CYP2C19 P33261 1/20 0.34
TNKS2 Q9H2K2 1/20 0.34
ERN1 O75460 1/20 0.34
APOBEC3A P31941 1/20 0.34
APOBEC3G Q9HC16 1/20 0.34
BACE1 P56817 1/20 0.33
NQO1 P15559 1/20 0.33
HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28816096 0.81 CYP1A2 (0.52) CYP1A2CYP2A6ALDH1A1HSD17B10HPGD
SCHEMBL11208225 0.79 CYP1A2 (0.59) CYP1A2CYP2A6ALDH1A1HSD17B10HPGD
SCHEMBL28799309 0.79 ALDH1A1 (0.41) CYP1A2ALDH1A1HSD17B10HPGDKDM4E
SCHEMBL1161428 0.77 CYP2A6 (0.57) CYP1A2CYP2A6ALDH1A1HPGDKDM4E
SCHEMBL27995615 0.76 KDM4E (0.38) CYP1A2CYP2A6ALDH1A1HPGDKDM4E
SCHEMBL2499216 0.75 CYP1A2 (0.50) CYP1A2CYP2A6ALDH1A1HSD17B10HPGD
SCHEMBL7654734 0.74 CYP1A2 (0.53) CYP1A2CYP2A6ALDH1A1HSD17B10HPGD
SCHEMBL15914806 0.73 CYP1A2 (0.52) CYP1A2CYP2A6ALDH1A1HSD17B10HPGD
SCHEMBL17599016 0.72 CYP1A2 (0.52) CYP1A2CYP2A6ALDH1A1HSD17B10KDM4E
SCHEMBL27977447 0.71 CYP1A2 (0.50) CYP1A2CYP2A6ALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108699003-A Prepare the catalytic hydrogenation of pyrazoles 巴斯夫欧洲公司 2018-10-23 CN disclosed
CN-107827783-A Method for continuously preparing sulfonated product of benzene series by using micro-reaction device 南京工业大学 2018-03-23 CN disclosed
CN-104303317-A Etching solution and method for producing silicon substrate using same WAKO PURE CHEM IND LTD 2015-01-21 CN disclosed