Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.53 |
| ▸ | LTA4H | P09960 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11208225 | 0.94 | CYP1A2 (0.59) | CYP1A2CYP2A6TSHRLMNAL3MBTL1 | |
| SCHEMBL1161428 | 0.80 | CYP2A6 (0.57) | CYP1A2CYP2A6LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL12925863 | 0.77 | LTA4H (0.57) | LTA4HTSHRL3MBTL1HPGDHTT | |
| SCHEMBL7654726 | 0.77 | LTA4H (0.46) | LTA4HTSHRLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL14204729 | 0.77 | RHEB (0.56) | CYP1A2CYP2A6LTA4HTSHRKDM4E | |
| SCHEMBL13886669 | 0.77 | KMT2A (0.49) | CYP1A2LTA4HTSHRLMNAL3MBTL1 | |
| SCHEMBL15914806 | 0.76 | CYP1A2 (0.52) | CYP1A2CYP2A6TSHRLMNAL3MBTL1 | |
| SCHEMBL2499216 | 0.74 | CYP1A2 (0.50) | CYP1A2CYP2A6TSHRALDH1A1KDM4E | |
| SCHEMBL27995366 | 0.74 | CYP1A2 (0.50) | CYP1A2CYP2A6TSHRLMNAL3MBTL1 | |
| SCHEMBL8517685 | 0.74 | LTA4H (0.52) | LTA4HTSHRLMNAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |