Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | TP53 | P04637 | 5/20 | 0.50 |
| ▸ | HTR6 | P50406 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.48 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31585998 | 0.93 | MAPT (0.56) | MAPTTP53LMNAKCNN4KCNA3 | |
| SCHEMBL533706 | 0.93 | MAPT (0.56) | MAPTTP53LMNAKCNN4KCNA3 | |
| SCHEMBL2704794 | 0.92 | KMT2A (0.56) | MAPTTP53HTR6KCNN4KCNA3 | |
| SCHEMBL4726759 | 0.90 | HTR6 (0.50) | MAPTTP53HTR6LMNAKCNN4 | |
| SCHEMBL26159157 | 0.82 | MAPT (0.51) | MAPTTP53HTR6LMNAKCNN4 | |
| SCHEMBL8466244 | 0.82 | KMT2A (0.53) | MAPTTP53HTR6LMNAKCNN4 | |
| SCHEMBL2705025 | 0.82 | PSEN1 (0.56) | MAPTTP53HTR6KCNN4KCNA3 | |
| SCHEMBL768700 | 0.81 | KCNN4 (0.67) | MAPTTP53HTR6LMNAKCNN4 | |
| SCHEMBL9538299 | 0.81 | ALDH1A1 (0.49) | MAPTHTR6LMNAKMT2APOLB | |
| SCHEMBL31585919 | 0.80 | MAPT (0.44) | MAPTTP53LMNAKCNN4KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104672213-A | Amide compound with antitumor activity, and application thereof | UNIV SHAANXI TECHNOLOGY | 2015-06-03 | — | — | CN | disclosed |