Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.62 |
| ▸ | TSHR | P16473 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.58 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.58 |
| ▸ | GBA1 | P04062 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3748887 | 0.83 | HTT (0.84) | ALDH1A1MAPK1MEN1KMT2ACYP1A2 | |
| SCHEMBL4059724 | 0.77 | MTOR (0.49) | LRRK2PIK3CAPIK3CDPIK3R1PIK3CB | |
| SCHEMBL2907994 | 0.77 | MTOR (0.54) | LRRK2PIK3CAPIK3CDPIK3CGSTK4 | |
| SCHEMBL4090305 | 0.77 | HTT (0.66) | ALDH1A1MAPK1MEN1KMT2ACYP1A2 | |
| SCHEMBL1083870 | 0.77 | LMNA (0.66) | ALDH1A1MAPK1MEN1KMT2ACYP1A2 | |
| SCHEMBL1083989 | 0.75 | HTT (0.74) | ALDH1A1MAPK1MEN1KMT2ACYP1A2 | |
| SCHEMBL1083793 | 0.75 | HTT (0.74) | ALDH1A1MAPK1MEN1KMT2ACYP1A2 | |
| SCHEMBL13342122 | 0.75 | HTT (0.74) | ALDH1A1MAPK1CYP1A2TSHRCYP3A4 | |
| SCHEMBL258434 | 0.74 | PIK3CA (1.00) | ALDH1A1MAPK1MEN1KMT2ACYP1A2 | |
| SCHEMBL19445385 | 0.74 | PIK3CA (0.68) | CLK4PIK3CAPIK3CDPIK3R1PIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104311494-A | m-(4-morpholinyl-2-quinazolinyl) benzamide compounds and synthetic method and application thereof | UNIV XI AN JIAOTONG | 2015-01-28 | — | — | CN | disclosed |
| CN-104311494-A | m-(4-morpholinyl-2-quinazolinyl) benzamide compounds and synthetic method and application thereof | UNIV XI AN JIAOTONG | 2015-01-28 | — | — | CN | disclosed |