Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | XBP1 | P17861 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.50 |
| ▸ | OXTR | P30559 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27995951 | 0.87 | MAPT (0.53) | MAPTHTTSMN1; SMN2NPSR1RECQL | |
| SCHEMBL27996173 | 0.86 | MAPT (0.60) | MAPTHTTTP53NPSR1LMNA | |
| SCHEMBL16265366 | 0.81 | SMN1; SMN2 (0.51) | MAPTHTTTP53SMN1; SMN2NPSR1 | |
| SCHEMBL16557449 | 0.76 | MAPT (0.65) | MAPTHTTTP53SMN1; SMN2NPSR1 | |
| SCHEMBL15145902 | 0.74 | SMN1; SMN2 (0.63) | MAPTTP53SMN1; SMN2LMNAKMT2A | |
| SCHEMBL17183514 | 0.74 | KMT2A (0.65) | MAPTNPSR1RECQLLMNAKMT2A | |
| SCHEMBL16557464 | 0.73 | SMN1; SMN2 (0.71) | MAPTHTTSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL8337234 | 0.73 | HCRTR2 (0.71) | MAPTSMN1; SMN2KMT2AALDH1A1MEN1 | |
| SCHEMBL16557491 | 0.73 | MAPT (0.66) | MAPTTP53KMT2AALDH1A1MEN1 | |
| SCHEMBL27996304 | 0.73 | RORC (0.62) | MAPTHTTTP53SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104220058-A | Serine racemase inhibitor | NAT UNIV CORP UNIV TOYAMA | 2014-12-17 | — | — | CN | disclosed |