Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.51 |
| ▸ | BAX | Q07812 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | TSPO | P30536 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2801681 | 0.92 | ALDH1A1 (0.61) | DNM1MAPTSMN1; SMN2P2RX3TP53 | |
| SCHEMBL2803193 | 0.86 | ALDH1A1 (0.56) | DNM1MAPTSMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL15571169 | 0.85 | DNM1 (0.56) | DNM1MAPTSMN1; SMN2P2RX3BAX | |
| SCHEMBL16241623 | 0.85 | DNM1 (0.65) | DNM1MAPTSMN1; SMN2P2RX3BAX | |
| SCHEMBL29448105 | 0.85 | DNM1 (0.65) | DNM1MAPTSMN1; SMN2P2RX3BAX | |
| SCHEMBL29556276 | 0.85 | DNM1 (0.44) | DNM1MAPTSMN1; SMN2P2RX3BAX | |
| SCHEMBL19056362 | 0.85 | DNM1 (0.44) | DNM1MAPTSMN1; SMN2P2RX3BAX | |
| SCHEMBL25492221 | 0.82 | DNM1 (0.57) | DNM1MAPTSMN1; SMN2P2RX3BAX | |
| SCHEMBL2801633 | 0.82 | DNM1 (0.43) | DNM1MAPTSMN1; SMN2P2RX3BAX | |
| SCHEMBL483188 | 0.81 | ALDH1A1 (0.54) | DNM1MAPTSMN1; SMN2TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10005787-B2 | Highly photo-stable bis-triazole fluorophores | NITTO DENKO CORPORATION (JP) | 2018-06-26 | — | — | US | disclosed |
| US-10005787-B2 | Highly photo-stable bis-triazole fluorophores | NITTO DENKO CORPORATION (JP) | 2018-06-26 | — | — | US | disclosed |
| US-20180002337-A1 | HIGHLY PHOTO-STABLE BIS-TRIAZOLE FLUOROPHORES | NITTO DENKO CORPORATION (JP) | 2018-01-04 | — | — | US | disclosed |
| US-20180002337-A1 | HIGHLY PHOTO-STABLE BIS-TRIAZOLE FLUOROPHORES | NITTO DENKO CORPORATION (JP) | 2018-01-04 | — | — | US | disclosed |
| WO-2016112220-A1 | HIGHLY PHOTO-STABLE BIS-TRIAZOLE FLUOROPHORES | NITTO DENKO CORPORATION (JP) | 2016-07-14 | — | — | WO | disclosed |
| US-9040718-B2 | Hybrid host materials for electrophosphorescent devices | THE UNIVERSITY OF ROCHESTER (US) | 2015-05-26 | — | — | US | disclosed |
| WO-2010085676-A1 | HYBRID HOST MATERIALS FOR ELECTROPHOSPHORESCENT DEVICES | UNIVERSITY OF ROCHESTER (US) | 2010-07-29 | — | — | WO | disclosed |
| US-20100184942-A1 | Hybrid Host Materials For Electrophosphorescent Devices | THE UNIVERSITY OF ROCHESTER | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180002337-A1 | HIGHLY PHOTO-STABLE BIS-TRIAZOLE FLUOROPHORES | CBR3, TPD52L2, TNS4 | DNM1 2752/4885MAPT 2483/4885SMN1; SMN2 4062/4885 |
| US-10005787-B2 | Highly photo-stable bis-triazole fluorophores | CBR3, TPD52L2, TNS4 | DNM1 2752/4885MAPT 2483/4885SMN1; SMN2 4062/4885 |
| US-20100184942-A1 | Hybrid Host Materials For Electrophosphorescent Devices | SLC29A2, SLC43A3, SLC29A1 | DNM1 2874/4885MAPT 218/4885SMN1; SMN2 3079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.