Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1132624 | 0.76 | IDO1 (0.57) | MAPTALDH1A1CA1CA2CA9 | |
| SCHEMBL29710420 | 0.76 | IDO1 (0.57) | MAPTALDH1A1CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL967050 | 0.74 | IDO1 (0.55) | MAPTALDH1A1CA1CA2CA9 | |
| Bromide SCHEMBL20984360 | 0.74 | IDO1 (0.55) | MAPTALDH1A1IDO1KDM4EPOLB | |
| Hydrochloric Acid SCHEMBL29502114 | 0.74 | IDO1 (0.55) | MAPTALDH1A1CA1CA2CA9 | |
| SCHEMBL3231268 | 0.73 | ALDH1A1 (0.50) | MAPTALDH1A1CA1CA2CA9 | |
| SCHEMBL17830372 | 0.73 | ALDH1A1 (0.50) | MAPTALDH1A1CA1CA2CA9 | |
| SCHEMBL8030121 | 0.73 | MAPT (0.50) | MAPTALDH1A1CA1CA2CA9 | |
| SCHEMBL16284442 | 0.73 | MAPT (0.55) | MAPTALDH1A1CA1CA2CA9 | |
| SCHEMBL27554865 | 0.72 | MEN1 (0.32) | MAPTALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104487433-A | Triazolone compounds as mpges-1 inhibitors | GLENMARK PHARMACEUTICALS SA | 2015-04-01 | — | — | CN | disclosed |