Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29056188 | 0.79 | MEN1 (0.50) | MEN1POLBKMT2AALDH1A1MAPT | |
| SCHEMBL27329147 | 0.73 | SLC22A12 (0.31) | MEN1POLBKMT2A | |
| SCHEMBL27577490 | 0.73 | ALDH1A1 (0.53) | ALDH1A1 | |
| SCHEMBL27996979 | 0.72 | MAPT (0.50) | MEN1POLBKMT2AALDH1A1MAPT | |
| SCHEMBL27286217 | 0.72 | ALDH1A1 (0.64) | MEN1POLBKMT2AALDH1A1MAPT | |
| SCHEMBL27296313 | 0.72 | MAPT (0.46) | MEN1POLBKMT2AALDH1A1MAPT | |
| SCHEMBL31527626 | 0.71 | MCL1 (0.50) | MEN1POLBKMT2AALDH1A1MCL1 | |
| SCHEMBL28623470 | 0.71 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL27839046 | 0.70 | CYP1A2 (0.44) | MEN1POLBKMT2AALDH1A1MAPT | |
| SCHEMBL28921996 | 0.65 | GAA (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1299365-A | Hygromycin A derivatives | PFIZER PROD INC (US) | 2001-06-13 | — | — | CN | disclosed |