Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.52 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.52 |
| ▸ | TRPM8 | Q7Z2W7 | 9/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | LDHB | P07195 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28245727 | 0.89 | CYP1A2 (0.48) | CDC7DBF4TRPM8 | |
| SCHEMBL15049531 | 0.86 | CDC7 (0.73) | CDC7DBF4TRPM8SMN1; SMN2BTK | |
| SCHEMBL28246576 | 0.84 | MAPT (0.50) | — | |
| SCHEMBL15049469 | 0.84 | TRPM8 (0.50) | TRPM8SMN1; SMN2KDM4EBTK | |
| SCHEMBL4294474 | 0.77 | HPGD (0.63) | CDC7DBF4SMN1; SMN2 | |
| SCHEMBL15049461 | 0.76 | CDC7 (0.64) | CDC7DBF4TRPM8KDM4EBTK | |
| SCHEMBL15049019 | 0.76 | TRPM8 (0.77) | CDC7DBF4TRPM8SMN1; SMN2KDM4E | |
| SCHEMBL3436646 | 0.75 | SMN1; SMN2 (0.70) | TRPM8SMN1; SMN2KDM4E | |
| SCHEMBL17318028 | 0.74 | CDC7 (0.73) | CDC7DBF4TRPM8SMN1; SMN2KDM4E | |
| SCHEMBL27774995 | 0.73 | CDC7 (0.52) | CDC7DBF4SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104220069-B | Trpm8 antagonists | 多姆皮制药公司 | 2018-10-02 | — | — | CN | claimed |
| CN-104220069-A | Trpm8 antagonists | DOMPE SPA | 2014-12-17 | — | — | CN | claimed |
| CN-104220069-A | Trpm8 antagonists | DOMPE SPA | 2014-12-17 | — | — | CN | disclosed |